Dr. ir. Martijn Starmans is Assistant Professor at Erasmus MC (Rotterdam, the Netherlands), where he leads the AI for Integrated Diagnostics (AIID) research line. He holds a dual appointment in the Department of Radiology & Nuclear Medicine (BIGR) and the Department of Pathology (PHANTOM).
His research focuses on developing clinically valuable, trustworthy, and scalable medical AI. A central theme throughout his work is that AI systems should learn not only from individual datasets, but also from prior studies, clinical applications, and existing knowledge. To this end, he develops automated machine learning, foundation-model-based, and multimodal AI methods that generalize across healthcare domains. His primary research interest is integrated diagnostics, combining information from radiology (“radiomics”) and pathology (“pathomics”) into unified AI systems (“radiopathomics”) to support precision oncology.
Martijn’s work spans multiple cancer types, including sarcoma, liver cancer, colorectal cancer, bladder cancer, melanoma, and neuroendocrine tumors. To establish his independent research line, he received a prestigious €2 million NGF AINed Personal Fellowship in 2024. Together with collaborators from the BCN-AIM Lab led by Prof. Karim Lekadir, he contributed to the development of the FUTURE-AI initiative for trustworthy medical AI. For his contributions to equitable and globally accessible medical AI, he received the MICCAI Health Equity Award.
Beyond methodological research, Martijn is actively involved in building the international medical AI community through leadership roles in open science, research infrastructure, and global collaboration. Together with Prof. Josien Pluim, he serves as General Chair of MICCAI 2030 in Rotterdam. The conference is organized by an international committee spanning 32 countries across all six continents and aims to advance clinically valuable, trustworthy, and globally accessible medical AI.
Martijn is co-founder and co-lead of the MICCAI SIG Open Data, which promotes the sharing and reuse of medical imaging datasets and benchmarks. Since its launch at MICCAI 2024, the initiative has become an annual event at MICCAI, bringing together researchers, clinicians, industry partners, and dataset creators through scientific presentations, keynote lectures, and community discussions on open data standards. To support underrepresented diseases and populations, he established the AFRICAI repository for sharing accepted Open Data datasets.
Martijn is one of the initiators and principal investigators of the Sarcoma Artificial Intelligence (SAI) consortium (grant awarded), the Liver AI (LAI) consortium (grant awarded), and project lead of the Colorectal Liver Metastases AI (COLIMA) consortium. Across these initiatives, 51 clinical centers, companies, professional societies, and patient organizations from 18 countries collaborate on developing clinically impactful AI solutions. He is also affiliated with the Trustworthy AI for MRI ICAI Lab.
Martijn has a strong affinity with research infrastructure and data sharing. Besides the MICCAI Open Data initiative, he contributes to several large international projects focused on enabling collaborative and trustworthy AI research. He is work package leader of AFRICAI-RI, a Pan-African research infrastructure for collaborative biomedical imaging and artificial intelligence; was work package leader of EuCanImage, which developed a European cancer imaging platform for AI in oncology; and EOSC4Cancer, which established foundations for large-scale European data-driven cancer research. Additionally, he serves as external advisor to RadioVal and contributes to EUCAIM, Europe’s federated cancer imaging infrastructure.
For a more complete overview of ongoing projects and collaborations, see his BIGR profile page.
Martijn obtained his PhD degree cum laude on February 1, 2022 with the thesis Streamlined Quantitative Imaging Biomarker Development: Generalization of Radiomics through Automated Machine Learning. Motivated by a fascination for automation and generalization, he developed the automated machine learning framework WORC, enabling the efficient development of radiomics models across a wide variety of clinical applications. This work is described in this publication and forms the basis of many subsequent methodological developments in automated machine learning for medical imaging.
His thesis was nominated for the Fredrik Philipsprijs 2023 for Best Dutch Radiology Thesis and was selected among the top five finalists.
Download my PhD Thesis.
Martijn co-founded two courses and has taught multiple courses within the BSc and MSc Technical Medicine programmes of Erasmus MC and TU Delft. He currently teaches within the MSc Applied Physics programme at TU Delft. He also contributed to the first AFRICAI Summer School as mentor and programme committee member, and to the inaugural Rotterdam Radiology AI Course organized by the Dutch Radiological Society.
Martijn enjoys mentoring the next generation of researchers and has supervised a large number of BSc, MSc, internship, and thesis projects across medical imaging, AI, and integrated diagnostics.
Download my (slightly outdated) resumé / CV .
PhD ''Streamlined Quantitative Imaging Biomarker Development'' ("cum laude"), 2022
Erasmus Medical Center, Rotterdam, the Netherlands
MSc Applied Physics, 2016
Delft University of Technology, Delft, the Netherlands
BSc Applied Physics, 2013
Delft University of Technology, Delft, the Netherlands
*Not officially mentioned as Co-PI due to formalities. Reference of formal applicant available upon request.
*Not officially mentioned as Co-PI due to formalities. Reference of formal applicant available upon request.
I will be the General Chair of MICCAI 2030 in Rotterdam, bringing together a global organizing committee from 32 countries across 6 continents to shape the future of clinically valuable, trustworthy, and impactful medical AI.
The 2026 MICCAI Open Data Special Issue marked several major milestones for the initiative, including recognition as an official MICCAI Special Interest Group (SIG), the introduction of Health Equity micro-grants, 29 submissions to the Open Data Track, and 16 accepted dataset papers advancing FAIR and inclusive medical AI research.
Great study to systematically benchmark various LLMs and prompting strategies to extract structured information from radiological and pathological reports across six use cases and multiple languages. These findings show that open-weight LLMs can extract structured data from clinical reports across diseases, languages, and institutions, offering a scalable approach for clinical data curation.
The first MELBA Special Issue arising from the MICCAI Open Data initiative, bringing together 13 openly accessible datasets from the 2024 and 2025 editions and advancing FAIR, inclusive, and data-centric medical AI research.
AFRICAI-RI is a €5M Horizon Europe project establishing Africa’s first federated medical imaging infrastructure. As Erasmus MC PI and Work Package Lead, I contribute to building the FAIR and federated infrastructure enabling collaborative AI research across Africa.
Tremendous effort of our sarcoma PhD team to review over 300 (!) papers on AI for STBT, indicating substantial gaps towards implementation in clinical practice and insights how to get there!
Very proud of the first paper of PhD candidate Erik Kemper! This paper advocates for value-based development of AI tools in radiology, emphasizing that their limited clinical adoption stems from issues of usefulness and trust. By incorporating early health technology assessments (HTA) into the AI tool lifecycle, this study shows how a systematic evaluation can enhance clinical relevance and facilitate adoption into practice.
Very proud of the first paper of PhD candidate Douwe Spaanderman! This study externally and prospectively validated a radiomics model for differentiating lipomas from atypical lipomatous tumors (ALTs) on MRI, incorporating automatic and minimally interactive segmentation methods to improve clinical feasibility. The model demonstrated strong diagnostic performance across three large cohorts, achieving AUCs of up to 0.89 and performing comparably to expert radiologists, potentially reducing the need for biopsies.
Liver cancer is one the most common cancers worldwide. Magnetic resonance imaging (MRI) plays an important role in its diagnosis, but due to the wide variety of malignant and benign liver lesions, accurate diagnosis can be extremely challenging and highly reader dependent. The Liver Artificial Intelligence (LAI) consortium will develop novel MRI analysis methods to support the diagnosis of liver lesions and thereby improve treatment decisions for the individual patient.
Very proud of the first paper of PhD candidate Xinyi Wan! This study aims to improve the preoperative classification of nerve sheath tumors using radiomics, a method that extracts quantitative data from medical images. By analyzing MRI scans, we seek to develop a more accurate way to distinguish between different types of nerve sheath tumors before surgery. Our findings could lead to better treatment planning and outcomes for patients with these tumors. This research has the potential to enhance the diagnostic process and contribute to more personalized care for individuals with nerve sheath tumors, ultimately benefiting the medical community and patients alike.
Interview for the Beeldspraak magazine of the department of Radiology and Nuclear Medicine of the Erasmus MC on my new AIID research line.
The aim of the AI for Integrated Diagnostics (AIID) research line is to join forces of radiomics and pathomics to create trustworthy models to aid clinicians in decision making. Read more on the project page or the news article on the grant.
Radiomics uses quantitative medical imaging features and AI to create predictive models which can be used as biomarkers. In this thesis, we have developped an adaptive radiomics framework to automatically optimize the radiomics workflow per application and demonstrate its use to create biomarkers in eight different clinical applications.
We work on various clinical applications with different clinicians, and various technical solutions within medical image analysis & AI. The projects range from very technical hybrid, to more clinical. There are usually too many projects to describe here. Currently, we do not have any predefined projects available, we expect these to soon be put online, but we always have more than enough ideas, so feel free to contact me for more information if you are interested in an internship / thesis! For an overview of some past projects, please see https://bigr.nl/open-projects/.
*With a joint appointment at the Departments of Radiology & Nuclear Medicine and Pathology, Martijn leads the AI for Integrated Diagnostics (AIID) research line. The AIID group develops clinically valuable, trustworthy, and scalable medical AI, with a focus on integrated diagnostics, multimodal learning, automated machine learning, and foundation-model-based approaches. By combining information from radiology (“radiomics”), pathology (“pathomics”), and other data sources, the group develops AI methods that generalize across diseases, institutions, and healthcare applications.
Research leadership & funding: Martijn established the AIID research line through a prestigious NWO NGF AINed Personal Fellowship (€2M). He is initiator and principal investigator of several national and international consortia, including the Liver AI (LAI) consortium (NWO OTP grant), the Sarcoma Artificial Intelligence (SAI) consortium (Hanarth Fonds grant), and a Health-Holland TKI grant on incidental pulmonary embolism. He further serves as work package leader within the Horizon projects EuCanImage, EOSC4Cancer, and AFRICAI-RI. Across these initiatives, more than 60 clinical centers, companies, professional societies, and patient organizations from over 30 countries collaborate to advance medical AI, data sharing, and clinical translation. Martijn additionally serves as external advisor of RadioVal and contributes to EUCAIM.
Open Science & Community Building: Martijn is co-founder and co-chair of the MICCAI Open Data initiative, which promotes the sharing, dissemination, and creation of high-quality medical imaging datasets. Following successful editions at MICCAI 2024, MICCAI 2025, and MICCAI 2026, the initiative was recognized as an official MICCAI Special Interest Group (SIG). As guest editor, he coordinated two MELBA special issues that together published 29 openly accessible datasets. His contributions to equitable and globally accessible medical AI were recognized through the MICCAI Health Equity Award.
International Leadership: Martijn serves as General Chair of MICCAI 2030 in Rotterdam together with Prof. Josien Pluim. Supported by an international organizing committee representing 32 countries across all six continents, MICCAI 2030 aims to advance clinically valuable, trustworthy, and globally impactful medical AI.
Trustworthy AI: Martijn is co-lead of the FUTURE-AI guidelines, an international multidisciplinary initiative providing recommendations for the development, evaluation, reporting, and deployment of trustworthy AI in healthcare.
Supervision & Mentoring: Martijn currently supervises 4 postdoctoral researchers, 12 PhD candidates, and 15 MSc students, and has supervised a large number of additional BSc, MSc, and internship projects throughout his career.
Extending the work of his PhD, Martijn’s research focused on generalization of radiomics biomarkers (conventional and deep learning based) using automated machine learning and meta-learning. He worked on a variety of clinical applications (e.g. sarcoma, liver cancer, colorectal cancer, bladder cancer, melanoma, cardiomyopathy, neuroendocrine tumors, CRPS).
Martijn will visit the group of Prof. Dr. Karim Lekadir to collaborate on AI for oncology and cardiac imaging within the context of the EuCanImage and euCanSHare consortia. While the main focus is on developing novel algorithms for (deep) radiomics, they will also work on federated learning, applying Martijn’s adaptive radiomics framework from his PhD to ``new’’ clinical applications, a second version of the FUTURE-AI guiding principles, and improving the clinical utility of (radiomics) AI tools.
Supervisors: Karim Lekadir
See extended description in the “about” section on this website.
Supervisors: Stefan Klein, Jan-Jaap Visser, Wiro Niessen